Which Is A True Statement Below Regarding Assessment Of Pain Or Distress In Mice:?

Which of the following statements is correct about the evaluation of pain or discomfort in mice? Minor changes in activity level and behavior are frequent signs of pain or suffering in mice; Despite the fact that it is suffering from a fairly uncomfortable condition, a mouse may seem and behave normally.

• The most prevalent way that mice show pain or discomfort is through substantial changes in activity level and behavior (B).
• A mouse’s grooming behavior will not change even if the mouse is in pain or suffering.
• D.

• It is reasonable to believe that mice exhibiting normal behavior are not experiencing pain or anguish.
• Rodents are genetically engineered to hide signals of discomfort or suffering since they are considered a ‘prey species.’

Which statement is true about pain and distress in experimental animals?

Which of the following statements concerning pain and discomfort in experimental animals is TRUE? Petitioning for the elimination of animal pain and distress at any costs. Animal pain and distress may add sources of nonexperimental variance into a study. The relief of animal pain and distress is not significant for disease states.

Is animal pain and distress alleviation relevant for Disease states?

It is not necessary to alleviate animal pain and distress in disease states; in fact, animal pain and distress have minimal influence on experimental parameters in general. A study’s use of animals in pain or discomfort may bring sources of non-experimental variance into the trial.

What factors make the assessment of pain and distress difficult in rodents?

What are the elements that make assessing pain and suffering in rodents so difficult to do? body size and shape inclination to conceal when perturbed tendency to freeze when perturbed all of the aforementioned all of the aforementioned

Why is assessing pain and or distress in rats sometimes difficult?

What causes it to be difficult to measure pain and/or discomfort in rats at times? Because rats may not usually show indicators of pain and/or discomfort, this is a valid concern.

Which statement is true regarding the conduct of surgery in rats?

Which of the following statements about the care protocols for rats having surgery is TRUE? Rats should have their cardiovascular and respiratory functions, as well as their body temperature, checked while they are under anesthesia. Before placing the rats in a bag and storing them in the necropsy freezer or cooler, you must ensure that they are truly dead.

Which statement is true regarding Freund’s complete adjuvant FCA )?

Which of the following statements is TRUE about Freund’s complete adjuvant (FCA)? An very low rate of side effects has been seen with FCA use. The mycobacterial concentration in FCA had no influence on the deleterious effects seen in animals treated with FCA. According to the USDA, the use of FCA in vaccines is a difficult and unpleasant technique.

Which of the following best describes the federally mandated alternatives search in an animal protocol quizlet?

When developing an animal protocol, which of the following best represents the goal of the legally mandated ″alternatives search″? A search for processes that might potentially replace the use of animals, lower the number of animals used, or modify the approach in order to alleviate animal suffering or discomfort is underway.

Which statement S is are true regarding the assessment of pain or distress in guinea pigs?

Which of the following statements is/are correct in regards to the evaluation of pain or suffering in guinea pigs: Guinea pigs that are suffering from a mild to moderately painful ailment may seem and act as if nothing is wrong. The most common indicator of discomfort in guinea pigs is aggressiveness toward humans who handle them.

Which statement is true regarding the assessment of pain or distress in rabbits?

Which of the following statements about the evaluation of pain or discomfort in rabbits is TRUE? A rabbit suffering from a somewhat painful ailment may seem and behave normally, or it may show minor changes in its activity level, depending on the severity of the disease.

Which statement is true regarding the assessment of pain or distress in gerbils?

Which of the following statements is correct about the evaluation of pain or discomfort in gerbils? Even when a gerbil is suffering from a mild to moderately uncomfortable ailment, it may seem and act normally. The most typical way that gerbils exhibit pain or discomfort is through changes in activity level and behavior.

Which statement is true regarding the conduct of surgery in gerbils?

Which of the following statements is correct about anesthesia in gerbils? Gas anesthesia using a vaporizer is the most appropriate method for achieving long-term anesthesia.

Which statement characterizes a routine clinical examination of rodents?

An ordinary rodent clinic visit is distinguished by which of the following characteristics? Appearance, behavior, and function should all be evaluated using different approaches. Which of the following statements concerning procedures for clinical assessment of mice with tumors is correct?

What is complete Freund’s adjuvant CFA?

2.2 Completing the adjuvant of a friend (CFA) CFA is a dessicated mycobacterium suspension in paraffin oil and mannide monooleate that causes inflammation, tissue necrosis, and ulceration in the body. In mice and rats, it can be administered subcutaneously by the paw or intraperitoneally through the abdomen. After the injection, it takes 24 hours for the effects to become apparent.

What are Freund’s incomplete and complete adjuvants?

Complete Freund’s Adjuvant, usually known as CFA, is a water-in-oil emulsion that comprises inactivated mycobacteria and other ingredients (Mycobacterium tuberculosis is most frequently used). Freund’s adjuvant, also known as incomplete Freund’s adjuvant, is the same as water in oil emulsion but does not include the mycobacteria pathogen.

What is in complete Freund’s adjuvant?

It is composed of heat-killed Mycobacterium tuberculosis encapsulated in non-metabolizable oils, which is known as Complete Freund’s Adjuvant (CFA) (paraffin oil and mannide monooleate). Because CFA includes trehalose 6,6′ dimycolate (TDM), it is able to trigger the Mincle enzyme.

Which statement is true regarding the assessment of pain or distress in hamsters?

Which of the following statements is correct about the evaluation of pain or discomfort in hamsters? A hamster suffering from a mild to moderately painful ailment may seem and behave in the same way as usual. The most common way that hamsters show pain or discomfort is through small changes in their activity level and behavior.

How do federal regulations address animal pain and distress in research?

What measures are taken by the federal government to address animal suffering and discomfort in research? When it is consistent with acceptable scientific standards, animal suffering and distress must be avoided or reduced to the greatest extent possible.

What information should be provided with the results of a database search for alternatives?

Written documentation of the search for alternatives must include the following basic information: methods of searching, databases examined, the date of the search and time spans covered, keywords and/or search strategy employed by the PI, and the results obtained from the search for alternatives.

Do animals in research experience pain and distress?

Animals are capable of feeling pain and misery. All individuals participating in the use of animals in research have an ethical and legal commitment to decrease or eliminate pain and suffering in research animals where doing so does not interfere with the achievement of the study objectives.